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In short, clinical data highlights the high prevalence of NPS and their worsening over the progression of AD ( Pathologies of NPS in AD patients Human macrostructure (CT, MRI) and microstructure imaging (such as diffusion MRI), as well as functional imaging (fMRI), has been applied to investigate the brain changes related to NPS in AD

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As previously mentioned, whilst low to moderate physiological levels of ROS are beneficial for several processes of wound healing pathophysiology, excess ROS can be deleterious

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The ubiquitin-proteasome system in neurodegeneration